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Robert Lemos Selected Research

4- dodecyl- N- (1,3,4- thiadiazol- 2- yl)benzenesulfonamide

3/2010Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.
6/2009In vitro and in vivo activity of novel small-molecule inhibitors targeting the pleckstrin homology domain of protein kinase B/AKT.

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Robert Lemos Research Topics

Disease

13Neoplasms (Cancer)
11/2019 - 01/2009
7Hypoxia (Hypoxemia)
11/2019 - 04/2009
2Colonic Neoplasms (Colon Cancer)
01/2019 - 01/2009
2Breast Neoplasms (Breast Cancer)
01/2016 - 03/2010
2Neoplasm Metastasis (Metastasis)
06/2011 - 07/2010
2Pancreatic Neoplasms (Pancreatic Cancer)
07/2010 - 06/2009
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2010 - 01/2009
1Fibrosis (Cirrhosis)
05/2016
1Hepatocellular Carcinoma (Hepatoma)
05/2016
1Non-alcoholic Fatty Liver Disease
05/2016
1Renal Cell Carcinoma (Grawitz Tumor)
01/2015
1Colorectal Neoplasms (Colorectal Cancer)
02/2013
1Melanoma (Melanoma, Malignant)
02/2013
1Weight Loss (Weight Reduction)
03/2010
1Glioma (Gliomas)
04/2009
1Adenocarcinoma
04/2009
1Lung Neoplasms (Lung Cancer)
01/2009
1Carcinogenesis
01/2009
1Type 2 Diabetes Mellitus (MODY)
01/2009
1Hyperglycemia
01/2009

Drug/Important Bio-Agent (IBA)

3Transcription Factors (Transcription Factor)IBA
11/2019 - 07/2010
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
03/2010 - 01/2009
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2019 - 04/2009
2CytokinesIBA
11/2019 - 05/2016
2Oxygen (Dioxygen)IBA
05/2016 - 06/2011
22- amino- 3- (4'- N,N- bis(2- chloroethyl)amino)phenylpropionic acid N-oxideIBA
07/2010 - 04/2009
24- dodecyl- N- (1,3,4- thiadiazol- 2- yl)benzenesulfonamideIBA
03/2010 - 06/2009
2PX-866IBA
01/2009 - 01/2009
1InterleukinsIBA
11/2019
1Interleukin-8 (Interleukin 8)IBA
11/2019
1Small Cytoplasmic RNAIBA
11/2019
1GlycogenIBA
11/2019
1RNA (Ribonucleic Acid)IBA
11/2019
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2019
1Ligases (Synthetase)IBA
05/2016
1UbiquitinIBA
05/2016
1Chemokine CCL5IBA
05/2016
1EnzymesIBA
01/2016
1Fructose-Bisphosphate Aldolase (Aldolase)IBA
01/2016
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2015
1DNA (Deoxyribonucleic Acid)IBA
01/2015
1VemurafenibIBA
02/2013
1PLX 4720IBA
02/2013
1Phosphatidylinositols (Phosphatidylinositol)IBA
02/2013
1MethyltransferasesIBA
02/2013
1Stem Cell FactorIBA
06/2011
1Plasminogen Activator Inhibitor 1IBA
06/2011
1Hypoxia-Inducible Factor 1IBA
03/2011
1Dihydrotachysterol (AT 10)IBA
07/2010
1Biomarkers (Surrogate Marker)IBA
07/2010
1Paclitaxel (Taxol)FDA LinkGeneric
03/2010
1Erlotinib Hydrochloride (CP 358,774)FDA Link
03/2010
1Protein Kinases (Protein Kinase)IBA
03/2010
1platelet protein P47 (pleckstrin)IBA
03/2010
1Small Interfering RNA (siRNA)IBA
04/2009
1Carbon Nanotubes (Carbon Nanotube)IBA
04/2009
1Proteins (Proteins, Gene)FDA Link
04/2009
1Glucose (Dextrose)FDA LinkGeneric
01/2009
1ral Guanine Nucleotide Exchange FactorIBA
01/2009
1Deoxyglucose (2 Deoxy D glucose)IBA
01/2009
1Pioglitazone (Actos)FDA Link
01/2009
1PPAR-gamma AgonistsIBA
01/2009
1Insulin (Novolin)FDA Link
01/2009

Therapy/Procedure

3Therapeutics
06/2011 - 04/2009
2Radiotherapy
03/2011 - 07/2010
1Chemoradiotherapy
07/2010
1Drug Therapy (Chemotherapy)
07/2010